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The amount of weight loss you can expect with tirzepatide varies depending on several factors, including your individual response to the medication, adherence to lifestyle changes (such as diet and exercise), and the presence of any underlying health conditions like type 2 diabetes or obesity

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GLP-1 RAs mimic the effects of native GLP-1, which increases insulin secretion, inhibits glucagon secretion, increases satiety, and slows gastric emptying

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Worsening diabetic retinopathy: Rapid improvement in blood sugar can temporarily worsen eye damage in diabetic patients